Selected References

Introduction

Here are all the papers referenced in the MCA Web plus some others that I found of sufficient interest to include. Since all the citations are hyper-linked to the entries in this page, the references here are not in alphabetical order, but rather in an arbitrary order. This is not a complete list of MCA references, for more complete lists please read the reviews cited below or do a bibliographic search.

Fundamental Papers

Kacser, H. & Burns, J.A. (1973) The control of flux. Symp. Soc. Exp. Biol. 27, 65-104.

Burns, J.A. (1971) Studies on complex enzyme systems. PhD thesis, Univ of Edinburgh, now on the Web.

Heinrich, R. & Rapoport, T.A. (1974) A linear steady-state treatment of enzymatic chains. General properties, control and effector strength., Eur. J. Biochem. 42, 89-95.

Burns, J.A., Cornish-Bowden, A., Groen, A.K., Heinrich, R., Kacser, H., Porteous, J.W., Rapoport, S.M., Rapoport T.A., Stucki, J.W., Tager, J.M., Wanders, R.J.A. & Westerhoff, H.V. (1985), Control of metabolic systems. Trends Biochem. Sci. 10, 16.

Theoretical Advances

Heinrich, R. & Rapoport, T.A. (1975) Mathematical analysis of multienzyme systems. II. Steady-state and transient control. BioSystems 7, 130-136.

Kacser, H. (1983) The control of enzyme systems in vivo: elasticity analysis of the steady state. Biochem. Soc. Trans. 11, 35-40.

Reder, C. (1988) Metabolic control theory: a structural approach. J. Theoret. Biol. 135, 175-201.

Westerhoff, H.V. & Chen, Y.-D. (1984) How do enzyme activities control metabolite concentrations? An additional theorem in the theory of metabolic control. Eur. J. Biochem. 142, 425-430

Westerhoff, H.V. & Kell, D.B. (1987) Matrix method for determining the steps most rate-limiting to metabolic fluxes in biotechnological processes. Biotechnol. Bioeng. 30, 101-107.

Fell, D.A. & Sauro, H.M. (1985) Metabolic control and its analysis. Additional relationships between elasticities and control coefficients. Eur. J. Biochem. 148, 555-561.

Sauro, H.M., Small, J.R. & Fell, D.A. (1987) Metabolic control and its analysis. Extensions to the theory and matrix method. Eur. J. Biochem. 165, 215-221.

Small, J.R. & Fell, D.A. (1989) The matrix method of metabolic control analysis: its validity for complex pathway structures. J. Theoret. Biol. 136, 181-197.

Hofmeyr, J.-H.S., Kacser, H. & van der Merwe, K.J. (1986) Metabolic control analysis of moiety-conserved cycles. Eur. J. Biochem. 155, 631-641.

Small, J.R. & Fell, D.A. (1989) The matrix method of metabolic control analysis: its validity for complex pathway structures. J. Theoret. Biol. 136, 181-197.

Cascante, M., Franco, R. & Canela, E.I. (1989a) Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. 1. Unbranched pathways. Math. Biosci. 94, 271-288.

Cascante, M., Franco, R., and Canela, E.I. (1989b), Use of implicit methods from general sensitivity theory to develop a systematic approach to metabolic control. 2. Complex systems. Math. Biosci. 94, 289-309 .

Giersch, C. (1988) Control analysis of metabolic networks. 1. Homogeneous functions and the summation theorems for control coefficients. Eur. J. Biochem. 174, 509-513.

Acerenza, L., Sauro, H.M. & Kacser, H. (1989) Control analysis of time-dependent metabolic systems. J. Theoret. Biol. 137, 423-444.

Kohn, M.C. & Chiang, E. (1982) Metabolic network sensitivity analysis. J. Theoret. Biol. 98, 109-126.

Markus, M. & Hess, B. (1990) Control of metabolic oscillations: unpredictability, critical slowing down, optimal stability and hysteresis. In Control of Metabolic Processes. (Cornish-Bowden, A. & Cárdenas, M. eds), Plenum Press, New York, pp. 303-313.

Westerhoff, H.V. & Kell, D.B. (1988) A control theoretic analysis of inhibitor titration assays of metabolic channeling. Comments Mol. Cell. Biophys. 5, 57-107.

Kell, D.B. & Westerhoff, H.V. (1990) Control analysis of organised multienzyme systems. In: Structural and organizational aspects of metabolic regulation, UCLA Symposia on Molecular and Cellular Biology, New Series, Vol 134 (P. Srere, M.E. Jones and C. Mathews, eds), pp. 273-289. Alan R. Liss, New York.

Kacser, H., Sauro, H.M. & Acerenza, L. (1990) Enzyme-enzyme interactions and control analysis. 1. The case of nonadditivity: monomer-oligomer associations. Eur. J. Biochem. 187, 481-491.

Sauro, H.M. & Kacser, H. (1990) Enzyme-enzyme interactions and control analysis. 2. The case of nonindependence: heterologous associations. Eur. J. Biochem. 187, 493-500.

Kholodenko, B.N. & Westerhoff, H.V. (1993) Metabolic channelling and control of the flux. FEBS Lett. 320, 71-74.

van Dam, K., van der Vlag, J., Kholodenko, B.N. & Westerhoff, H.V. (1993) The sum of the flux control coefficients of all enzymes on the flux through a group-transfer pathway can be as high as two. Eur. J. Biochem. 212, 791-799.

Cárdenas, M.L. & Cornish-Bowden, A. (1989) Characteristics necessary for an interconvertible enzyme cascade to generate a highly sensitive response to an effector. Biochem. J. 257, 339-345.

Small, J.R. & Fell, D.A. (1990) Covalent modification and metabolic control analysis. Modification to the theorems and their application to metabolic systems containing covalently modifiable enzymes. Eur. J. Biochem. 191, 405-411.

Schuster, S., Kahn, D. & Westerhoff, H.V. (1993) Modular analysis of the control of complex metabolic pathways. Biophys. Chem. 48, 1-17.

Westerhoff, H.V., Hofmeyr, J.-H.S. & Kholodenko, B.N. (1994) Getting to the inside of cells using metabolic control analysis. Biophys. Chem. 50, 273-283.

Meléndez Hevia, E., Torres, N.V., Sicilia, J. & Kacser, H. (1990) Control analysis of transition times in metabolic systems. Biochem. J. 265, 195-202.

Reviews

Cornish-Bowden, A. (1995) Metabolic control analysis in theory and practice. Adv. Mol. Cell Biol. 11, 21-64.

Fell, D.A. (1992) Metabolic control analysis – a survey of its theoretical and experimental development. Biochem. J. 286, 313-330.

Schuster, S. & Heinrich, R. (1992) The definitions of metabolic control analysis revisited. BioSystems 27, 1-15.

Kell, D.B., van Dam, K. & Westerhoff, H.V. (1989) Control analysis of microbial growth and productivity. Symp. Soc. Gen. Microbiol. 44, 61-93.

Books

Westerhoff, H.V. & van Dam, K. (1987) Thermodynamics and Control of Biological Free-energy Transduction. Amsterdam, Elsevier.

Cornish-Bowden, A. & Cárdenas, M.L. (eds.) (1990) Control of metabolic processes., New York, Plenum Press.

Fell, D. A. (1996) Understanding the Control of Metabolism.. London, Portland Press.

Heinrich, R. & Schuster, S. (1996) The regulation of cellular systems.. New York, Chapman & Hall.

Experimental

Groen, A.K., Wanders, R.J.A., Westerhoff, H.V., van der Meer, R. and Tager, J.M. (1982) Quantification of the contribution of various steps to the control of mitochondrial respiration. J. Biol. Chem. 257, 2754-2757.

Niederberger, P., Prasad, R., Miozzari, G. & Kacser, H. (1982) A strategy for increasing an in vivo flux by genetic manipulations. The tryptophan system of yeast. Biochem. J. 287, 473-479.

Flint, H.J., Tateson, R.W., Barthelmess, I.B., Porteous, D.J., Donachie, W.D. and Kacser, H. (1981) Control of the flux in the arginine pathway of Neurospora crassa. Modulations of enzyme activity and concentration. Biochem. J 200, 231-246.

Torres, N.V., Mateo, F., Meléndez-Hevia, E. & Kacser, H. (1986) Kinetics of metabolic pathways. A system in vitro to study the control of flux. Biochem. J. 234, 169-174.

Small, J.R. (1993) Flux control coefficients determined by inhibitor titration: the design and analysis of experiments to minimize errors Biochem. J. 296, 423-433.

Brown, G.C., Hafner, R.P. & Brand, M.D. (1990) A 'top-down' approach to the determination of control coefficients in metabolic control theory. Eur. J. Biochem. 188, 321-325.

Delgado, J. & Liao, J.C. (1992), Determination of flux control coefficients from transient metabolite concentrations Biochem. J. 282, 919-927.

Delgado, J., and Liao, J.C. (1992), Metabolic control analysis using transient metabolite concentrations. Determination of metabolite concentration control coefficients. Biochem. J. 285, 965-972.

Groen, A.K., van Roermund, C.W.T., Vervoorn, R. & Tager, J.M. (1986), Control of gluconeogenesis in rat liver cells. Flux control coefficients of the enzymes in the gluconeogenic pathway in the absence and presence of glucagon. Biochem. J. 237, 379-389.

Software

Mendes, P. (1993) GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systems. Comput. Appl. Biosci. 9, 563-571.

Letellier, T., Reder, C. & Mazat, J. P. (1991) CONTROL – software for the analysis of control of metabolic networks. Comput. Applic. Biosci. 7, 383-390.

Thomas, S. & Fell, D.A. (1993) A computer program for the algebraic determination of control coefficients in metabolic control analysis. Biochem. J. 292, 351-360.

Sauro, H. M. (1993) SCAMP: a general-purpose simulator and metabolic control analysis program. Comput. Appl. Biosci. 9, 441-450.

Sauro, H.M. & Fell, D.A. (1991) SCAMP: A metabolic simulator and control analysis program. Math. Comput. Modelling 15, 15-28.

Cornish-Bowden, A. & Hofmeyr, J.-H.S. (1991), MetaModel: a program for modelling and control analysis of metabolic pathways on the IBM PC and compatibles. Comput. Applic. Biosci. 7, 89-93.

Ehlde, M. & Zacchi, G. (1995). MIST: a user-friendly metabolic simulator. Comput. Appl. Biosci. 11, 201-207.

Related Topics

Reich, J.G. & Sel'kov, E.E. (1981) Energy metabolism of the cell. A theoretical treatise. Academic Press, London.

Keleti, T. (1986) Basic enzyme kinetics., Akadémiai Kiadó, Budapest.

Cornish-Bowden, A. (1995) Fundamentals of enzyme kinetics. (2nd edition) Portland Press, London

Srere, P.A. (1987) Complexes of sequential metabolic enzymes. Ann. Rev. Biochem. 56, 21-56.

Ovádi, J. (1991) Physiological significance of metabolic channelling. J. Theoret. Biol. 152, 1-22.

Mendes, P., Kell, D.B. & Welch, G.R. (1995) Metabolic channeling in organized enzyme systems: experiments and models. Adv. Mol. Cell Biol. 11, 1-19.

Stucki, J.W. (1978). Stability analysis of biochemical systems. A practical guide. Progr. Biophys. Mol. Biol. 33, 99-187.

Chock, P.B. & Stadtman, E.R. (1980) Covalently interconvertible enzyme cascade systems. Methods Enzymol. 64, 297-325.


Last updated: March 28, 2013 at 15:59 pm