Dr J. William Allwood

 

 

 

 

 

 






Dr J. William Allwood
PDRA EU META-PHOR project,
Laboratory for Bioanalytical Spectroscopy,
Manchester Interdisciplinary Biocentre,
The University of Manchester,
131 Princess Street,
Manchester
,

M1 7DN

UK

 

 

 

Personal

 

 

 

 

Dr J. William Allwood

Manchester Interdisciplinary Biocentre, The University of Manchester,            

131 Princess Street, Manchester M1 7DN

Tel: +44 (0)161 306 4414

E-mail: William.Allwood@manchester.ac.uk

 

Place of birth: Shrewsbury, Shropshire, UK   

Date of birth: 1st September, 1979

 

 

Education

 

 

 

 

Bishops Castle Community College

Ten GCSE’s and three A levels in Chemistry, Biology and Geography


University of Wales, Aberystwyth

BSc (Hons) Microbiology Class 2:1, with First class dissertation (87%) on the rapid characterisation of urinary tract infection bacteria using MALDI-TOF-MS and multivariate analysis.  

PhD Metabolomics / Plant pathology; thesis title 'Plant-pathogen interactions are a biochemically rich, novel and challenging target for metabolomic approaches'.  This was under the guidance and supervision of Dr Luis A.J. Mur and Prof. Roy Goodacre.  We developed a novel dual-metabolomics system based upon the biochemical analysis of both pathogen and host during the interaction of Arabidopsis thaliana with various strains of Pseudomonas syringae pv. tomato. We also generated metabolomic profiles from; Brachypodium distachyon plants when challenged by pathogenic and resistance eliciting strains of Magnaporthe grisea (rice blast disease), and from genetically modified A. thaliana plants expressing individual bacterial avirulence genes under the control of chemical induced gene switches. 

 

 

Recent and Future Publications

 

 

Allwood, J.W., Ellis, D.I., Heald, J.K., Goodacre, R., Mur, L.A.J. (2006). Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea. The Plant Journal, 46, 351-368. (Full Text).

 

Ellis, D.I., Dunn, W.B., Griffin, J.L., Allwood, J.W., Goodacre, R. (2007). Metabolic fingerprinting as a diagnostic tool.  Pharmacogenomics 8(9): 1243 -1266 (Full Text).

 

Allwood, J.W., Ellis, D.I., Goodacre, R. (2008). Metabolomic Instrumentation and its application to the Analysis of Plants and Plant-host Interactions, Its Present Status and Future Potential. Physiologia Plantarum (In Press).

 

Holton, N.J., Allwood, J.W., Mur, L.A.J.  The auxin receptor TIR1 is involved in the establishment of systemic acquired resistance in A. thaliana.  Plant Journal (In Preparation).

 


Proceedings:

 

 Allwood, J.W., Lloyd, A.J., Goodacre, R., Mur, L.A.J. FT-IR analysis of plants and plant-

 pathogen interactions.  FT-IR diagnostics Forum - Workshop, (Robert Koch Institute,

 Berlin, Germany, 26-27 October, 2007).

 

Allwood, J.W., Dunn, W.B., Goodacre, R. (2007). Poster Presentation: META-PHOR Partner 5 Initial Investigations.  The Third International Conference of the Metabolomics Society (University of Manchester, UK, 10-14 June, 2007).

 

Allwood, J.W., Dunn, W.B., Wong, S.C.C., Jarvis, R., Heald, J.K., Gaskell, S.J., Goodacre, R., Mur L.A.J. (2005). Dual metabolomic analysis of Arabidopsis thaliana cell suspension cultures challenged by Pseudomonas syringae pv. tomato.  The First International Conference of the Metabolomics Society (Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan, 20-23 June, 2005).

 

Allwood, J.W., Dunn, W.B., Wong, S.C.C., Jarvis, R., Heald, J.K., Gaskell, S.J., Goodacre, R., Mur L.A.J. (2005). Dual metabolomic analysis of Arabidopsis thaliana cell suspension cultures challenged by Pseudomonas syringae pv. tomato.  All Wales Microbiology Meeting (Gregynog Hall, Newtown, 12-13 March, 2005). 

 

Allwood, J.W., Dunn, W.B., Wong, S.C.C., Jarvis, R., Heald, J.K., Gaskell, S.J., Goodacre, R., Mur L.A.J. (2004). Dual metabolomic analysis of Arabidopsis thaliana cell suspension cultures challenged by Pseudomonas syringae pv. tomato.  Plant Science Wales (University of Wales Swansea, 13-14 December, 2004).

 

Allwood, J.W., Ellis, D.I., Heald, J.K., Goodacre, R., Mur, L.A.J. (2004).

Poster presentation: Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea.  Society for Experimental Biology Annual Main Meeting (Heriot-Watt, Edinburgh, 29 March – 2 April, 2004).

 

Allwood, J.W., Ellis, D.I., Heald, J.K., Goodacre, R., Mur, L.A.J. (2003).

Poster presentation: Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea.  British Society of Plant Pathology Presidential Meeting (University of Nottingham, 15-18 December, 2003). 

 

 

 

 

 

Miscellaneous

 

 

 

 

I am a member of the Society for Experimental Biology (SEB) and also the Metabolomics society. I have a variety of interests including the detection and identification of plant derived metabolites using a combination of the many hyphenated analytical techniques available to our group (FT-IR and Raman spectroscopy’s, and GC-MS, GCxGC-MS, HPLC-MS, UPLC-MS, MALDI-MS, LDI-MS, DIMS, FT-ICR-MS, and OrbiTrap MS).

After having been schooled and worked in the picturesque South Shropshire countryside (Bishops Castle) for 20 years, I moved to Aberystwyth (Ceredigion) where I studied for my BSc and PhD.  I have since worked as a post-doctoral research associate for the Wheat Pathogenesis team at Rothamsted Research and the Bioanalytical Spectroscopy group at the University of Manchester on an EU funded project, META-PHOR - Metabolomic Technology Applications for Plants, Health and Outreach (Hall, 2007). 


My interests outside work include: listening to music (live and recorded) and playing my guitars; reading (mainly non-fiction); comedy (live and recorded); mountain biking and badminton.  I have also travelled around a number of European countries and visited Japan. I enjoy eating out as well as fine malt whiskeys, beers and ales -
German beer guide to Manchester.

 

 

Contact Details

 

 

 

 

If you wish to contact me, please use the following contact details:

E-mail:

 

William.Allwood@manchester.ac.uk

Address:

Laboratory for Bioanalytical Spectroscopy,
Manchester Interdisciplinary Biocentre,

The University of Manchester,

131 Princess Street,

Manchester,

M1 7DN
United Kingdom

 


Personal | Education | Publications | Miscellaneous | Contact

Last update: 17th October 2007

William.Allwood@manchester.ac.uk