|
Dr
David Ian Ellis
Senior Experimental Officer / Lab Manager
Manchester Interdisciplinary Biocentre
University of Manchester
131, Princess St
Manchester M1 7DN |
 |
 |
Personal |
 |
|
|
|
|
Dr David Ian Ellis
Manchester Interdisciplinary Biocentre, The
University of Manchester, 131, Princess St, Manchester M1 7DN
Tel: +44 (0)161 306 4485
Email:
|
|
 |
Education |
 |
|
|
|
|
Pembrokeshire
College, Pembrokeshire (Student of the year) BTEC National
Diploma in Science (Health Studies) Distinctions in all final year
modules.
University
of Wales, Aberystwyth BSc (Hons) Environmental Science Class
2:1, with First for dissertation on the health impacts of long-range
transboundary air pollution.
University
of Wales, Aberystwyth PhD FT-IR/Microbiology; thesis title
'Rapid Detection of Food Spoilage using Vibrational Spectroscopy and
Machine Learning'. This was under the guidance and supervision of Prof. Roy Goodacre
were we developed a novel method for the extremely rapid (seconds as
opposed to current techniques which take hours), accurate and
quantitative method for the detection of bacterial spoilage of muscle
foods.
|
|
|
|
Recent Publications |
 |
|
|
|
|
Ellis, D.I., Brewster, V.L. and Goodacre, R. (2010)
Fingerprinting food: rapid detection science for foods and
feedstuffs. Chemical Society
Reviews (in preparation).
Dunn, W.B., Broadhurst, D., Ellis, D.I.,
Brown, M, Halsall, A, O'Hagan, S, Spasic, I, Tseng, A. and Douglas B
Kell. (2008) A GC-TOF-MS study of the stability of serum and urine
metabolomes during the UK Biobank sample collection and preparation
protocols. International Journal of Epidemiology. 37,
i23-i30 DOI: 10.1093/ije/dym281 (Full
Text)
Allwood, J.W., Ellis, D.I. and Goodacre, R. (2008) Metabolomic Analysis
of Plants and Plant-Host Interactions: Technology, present status and
future potential. Physiologia Plantarum. 132,
117-135. DOI:10.1111/j.1399-3054.2007.01001.x (Full
Text)
Ellis, D.I., Dunn, W.B., Griffin, J.L., Allwood, J.W. and Goodacre, R.
(2007) Metabolic
Fingerprinting as a Diagnostic Tool. Pharmacogenomics, 8(9),
1243-1266. (Full Text)
Dunn, W.B., Broadhurst, D.I., Deepak, S.M., Buch, M.H., McDowell, G.,
Spasic, G., Ellis, D.I., Brooks, N., Neyses, L. & Kell D.B.
(2007) Serum metabolomics reveals many novel metabolic markers of heart
failure, including pseudouridine and 2-oxoglutarate. Metabolomics
3(4), 413-426. DOI:
10.1007/s11306-007-0063-5 (Full Text)
Goodacre, R., Roberts, L., Ellis, D.I., Thorogood, D., Reader, S.M.,
Ougham, H. & King, I. (2007) From phenotype to genotype: whole
tissue profiling for plant breeding. Metabolomics, 3(4),
489-501. DOI: 10.1007/s11306-007-0062-6 (Full Text)
Deepak, S., Dunn, W.B., Broadhurst, D., Buch, M., McDowell, G., Ellis,
D.I., Brooks, N., Kell, D.B. and Neyses, L. (2007) Serum metabolomic
analysis successfully discriminates heart failure patients from
controls, Heart, 93, A78-A79
Ellis, D.I., Broadhurst, D., Rowland, J.J. and Goodacre, R. (2007)
Rapid detection method for microbial spoilage using FT-IR and machine
learning. In: Rapid Methods (for Food and Feed Quality
Determination) (Eds: van Amerongen, A., Barug, D and
Lauwaars, M.) Wageningen Academic Publishers, Wageningen, Netherlands,
pp. 73-84
Wilkinson, S.J., Spasic, I. and Ellis, D.I. (2006) Genomes to Systems
3, Metabolomics, 2(3), 165-170.
DOI: 10.1007/s11306-006-0030-6 (Full Text)
Kenny, L.C., Harding, K.E.L., Ellis, D.I., Broadhurst, D., Dunn, W.B.,
Kell, D.B. and Baker, P.N. (2006) Rapid high-throughput detection of
preeclampsia, Journal of the Society for Gynecologic
Investigation, 13(2), 124A-125A
Ellis, D.I. and Goodacre, R. (2006) Metabolic fingerprinting in disease
diagnosis: biomedical applications of infrared and Raman spectroscopy, Analyst,
131, 875-885. DOI:10.1039/b602376m
(Full
Text)
Ellis, D.I and Goodacre, R. (2006) Quantitative detection and
identification methods for microbial spoilage, In Food
Spoilage Microorganisms (Ed. Blackburn, C), Woodhead
Publishing, Cambridge, UK, pp. 3-27. (Synopsis
and Contents)
Allwood, J.W., Ellis, D.I., Heald, J., Goodacre, R and Muir, L. (2006)
Metabolomic approaches reveal that phosphatidic and phosphatidyl
glycerol phospholipids are major discriminatory metabolites in
responses by Brachypodium distachyon to challenge
by Magnaporthe grisea. The Plant Journal, 46,
351-368. DOI:
10.1111/j.1365-313X.2006.02692.x (Full
Text)
Underwood, B.R., Broadhurst, D., Dunn, W.B., Ellis, D.I., Michell,
A.W., Vacher, C., Mosedale, D.E., Kell, D.B., Barker, R., Grainger,
D.J. and Rubinsztein, D.C. (2006) Huntington disease patients and
transgenic mice have similar pro-catabolic serum metabolite profiles, Brain,
129(4), 877-886. (Full Text)
Zhao, H.J., Parry, R.L., Ellis, D.I., Griffith, G.W. and Goodacre, R.
(2006) Rapid differentiation of Streptomyces
isolates using Fourier transform infrared spectroscopy, Vibrational
Spectroscopy, 40, 213-218. (Full Text)
Ellis, D.I., Broadhurst, D., Clarke, S.J. and Goodacre, R. (2005) Rapid
identification of closely related muscle foods by vibrational
spectroscopy and machine learning. Analyst, 130(12),
1648-1654. (Full Text)
Jenkins, T.E., Hayton, D., Ellis, D.I., Bailey, P., Noakes, T.C.Q. and
Clark, G.F. (2005) Multi-technique study of silicon dioxide films on
4H-SiC, Recent Research Developments in Physical Chemistry,
8(2005), 1-20.
Kenny, L.C., Dunn, W.B., Ellis, D.I., Myers, J., Baker, P.N and the
GOPEC Consortium, & Kell, D.B. (2005) Novel biomarkers for
pre-eclampsia detected using metabolomics and machine learning, Metabolomics,
1(3), 227-234. (Full Text)
Kenny, L.C., Dunn, W.B., Ellis, D.I., Myers, J.E., Robinson, A.E.,
Kell, D.B. and Baker, P.N. (2005) Novel biomarkers for preeclampsia
detected using metabolomics and machine learning. Journal of
the Society for Gynecologic Investigation, 12(2),
355 Suppl. S FEB 2005
Kenny, L.C., Dunn, W.B., Ellis, D.I., Myers, J.E., Robinson, A.E.,
Kell, D.B. and Baker, P.N. (2005) Alterations in placental hemodynamics
in growth-restricted transgenic mice. Journal of the Society
for Gynecologic Investigation, 12(2), 354
Suppl. S FEB 2005
Dunn, W.B. and Ellis, D.I. (2005) Metabolomics: current analytical
platforms and methodologies. Trends in Analytical Chemistry 24(4),
285-294. (Full Text)
Brown, M., Dunn, W.B., Ellis, D.I., Goodacre, R., Handl, J., Knowles,
J.D., O'Hagan, S., Spasic, I. and Kell, D.B. (2005) A metabolome
pipeline: from concept to data to knowledge. Metabolomics 1(1),
39-51. (Full Text)
Ellis, D.I., O'Hagan, S., Dunn, W.B., Brown, M. and Vaidyanathan, S.
(2004) From genomes to systems. Genome Biology 5(11),
354. (Full Text)
Ellis, D.I., Broadhurst, D. and Goodacre, R. (2004) Rapid and
quantitative detection of the microbial spoilage of beef by Fourier
transform infrared spectroscopy and machine learning. Analytica
Chimica Acta 514, 193-201. (Full Text)
Naheed N. Kaderbhai, David I. Broadhurst, David I. Ellis, Royston
Goodacre and Douglas B. Kell. (2003) Functional genomics via metabolic
footprint profiling: Monitoring metabolite secretion by Escherichia
coli tryptophan metabolism mutants using FT-IR and Direct Injection
Electrospray Mass Spectrometry. Comparitive and Functional Genomics
4, 376-391. (Abstract)
(Full Text)
Ellis, D.I., Harrigan, G.G. and Goodacre, R. (2003) Metabolic
Fingerprinting with Fourier Transform Infrared Spectroscopy. In:
Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function
Analysis (Eds: Harrigan, G.G. and Goodacre, R.)Kluwer Academic, Boston,
2003, pp. 111-124. (Synopsis
and contents and ordering
info)
Ellis, D.I., Broadhurst, D., Kell, D.B., Rowland, J.J. and Goodacre, R.
(2002)
Rapid and quantitative detection of the microbial spoilage of meat by
Fourier transform infrared spectroscopy and machine learning. Applied
and Environmental Microbiology 68 (6),
2822-2828. (PubMed
abstract) (Full
text)
Ellis, D.I. and Goodacre, R. (2001)Rapid and quantitative detection
of the microbial spoilage of muscle foods: current status and future
trends. Trends in Food Science and Technology 12 (11),
414-424. (Full text)
Proceedings:
Grube, M., Clarke, S., Jarvis, R.M., Ellis, D.I., Goodacre, R.,
Matjuskova, N. and Muiznieks, I. (2003) Studies of mushrooms Lentinula
edodes by infrared spectroscopy. The Inaugral
Austral-Asian Biospectroscopy Conference (ABC), 3-7 February,
2003.
Grube, M., Goodacre, R., Matjuskova, N., Muiznieks, I., Clarke, S.,
Jarvis, R.M. and Ellis, D.I. (2003) Nutritional studies of some Lentinula
edodes strains by infrared and Raman spectroscopy. 11th
European Congress on Biotechnology, 24-29 August, 2003.
Grube, M., Goodacre, R., Jarvis, R.M., Matjuskova, N., Muiznieks, I.,
Clarke, S. and Ellis, D.I. (2003) Studies of carbohydrate content in Lentinula
edodes mycelium by infrared and Raman spectroscopy. XIV
Congress of European Mycologists, 22-27 September, 2003. |
|
| |
Miscellaneous |
|
|
|
|
|
I am a member of the Society for General
Microbiology (SGM)
and the Institute of Biology
(IoB) and have a
variety of interests including
the detection and identification of metabolites using a combination of
the many hyphenated analytical
techniques available to our group.
After 11 years in rural Wales (three in Pembrokeshire
and eight in Borth, Ceredigion ), I returned to the
North-West and now live in a village to the South of Manchester and on
the edge of the Cheshire plain.
My interests outside work includes: music
(rock/reggae/dancehall/indie/alternative/post-punk/world/electronica),
the great outdoors, travel, reading, art (especially painting,
photography, and
sculpture), gigs,
gym,
power yoga,
Hatha yoga,
Buddhist meditation,
badminton,
walking, cooking, cinema , galleries,
abseiling ,
and (very
amateur) photography.
|
|
|
|
Contact Details |
|
|
|
|
|
If you wish to contact me, please use the
following contact details:
| E-mail: |
|
| Address: |
School of Chemistry
Manchester Interdisciplinary Biocentre
University of Manchester
131, Princess St
Manchester M1 7DN
United Kingdom
|
|
|
|
|
| |
Group |
|
|
 |
|
|
Back to the group's homepage. |
|
|
