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Dr David Ian Ellis
Senior Experimental Officer / Lab Manager
Manchester Interdisciplinary Biocentre
University of Manchester
131, Princess St
Manchester M1 7DN
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Personal |
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Dr David Ian Ellis
Manchester Interdisciplinary Biocentre,
The University of Manchester, 131, Princess St, Manchester M1 7DN
Tel: +44 (0)161 306 4485
Email:
Place of birth: Leigh, Greater Manchester, UK.
Date of birth: 28 June 1964
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Education |
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Pembrokeshire College,
Pembrokeshire (Student of the year) BTEC National Diploma in Science
(Health Studies) Distinctions in all final year modules.
University of Wales, Aberystwyth BSc (Hons) Environmental Science Class 2:1, with First for
dissertation on the health impacts of long-range transboundary air pollution.
University of Wales, Aberystwyth PhD FT-IR/Microbiology; thesis title 'Rapid Detection of
Food Spoilage using Vibrational Spectroscopy and Machine Learning'. This was under the guidance and supervision of Prof. Roy Goodacre were we developed a novel method for the extremely rapid (seconds as opposed to current techniques which take hours), accurate and quantitative method for the detection of bacterial spoilage of muscle foods.
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Recent Publications |
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Dunn, W.B., Broadhurst, D., Ellis, D.I., Brown, M, Halsall, A, O'Hagan, S, Spasic, I, Tseng, A. and Douglas B Kell. (2008) A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols. International Journal of Epidemiology. 37, i23-i30 DOI: 10.1093/ije/dym281 (Full Text)
Allwood, J.W., Ellis, D.I. and Goodacre, R. (2007) Metabolomic Analysis of Plants and Plant-Host Interactions: Technology, present status and future potential. Physiologia Plantarum. 132, 117-135. DOI:10.1111/j.1399-3054.2007.01001.x (Full Text)
Ellis, D.I., Dunn, W.B., Griffin, J.L., Allwood, J.W. and Goodacre, R. (2007) Metabolic
Fingerprinting as a Diagnostic Tool. Pharmacogenomics, 8(9), 1243-1266. (Full Text)
Dunn, W.B., Broadhurst, D.I., Deepak, S.M., Buch, M.H., McDowell, G., Spasic, G., Ellis, D.I., Brooks, N., Neyses, L. & Kell D.B. (2007) Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate. Metabolomics 3(4), 413-426. DOI: 10.1007/s11306-007-0063-5 (Full Text)
Goodacre, R., Roberts, L., Ellis, D.I., Thorogood, D., Reader, S.M., Ougham, H. & King, I. (2007) From phenotype to genotype: whole tissue profiling for plant breeding. Metabolomics, 3(4), 489-501. DOI: 10.1007/s11306-007-0062-6 (Full Text)
Deepak, S., Dunn, W.B., Broadhurst, D., Buch, M., McDowell, G., Ellis, D.I., Brooks, N., Kell, D.B. and Neyses, L. (2007) Serum metabolomic analysis successfully discriminates heart failure patients from controls, Heart, 93, A78-A79
Ellis, D.I., Broadhurst, D., Rowland, J.J. and Goodacre, R. (2007) Rapid detection method for microbial spoilage using FT-IR and machine learning. In: Rapid Methods (for Food and Feed Quality Determination) (Eds: van Amerongen, A., Barug, D and Lauwaars, M.) Wageningen Academic Publishers, Wageningen, Netherlands, pp. 73-84
Wilkinson, S.J., Spasic, I. and Ellis, D.I. (2006) Genomes to Systems 3, Metabolomics, 2(3), 165-170. DOI: 10.1007/s11306-006-0030-6 (Full Text)
Kenny, L.C., Harding, K.E.L., Ellis, D.I., Broadhurst, D., Dunn, W.B., Kell, D.B. and Baker, P.N. (2006) Rapid high-throughput detection of preeclampsia, Journal of the Society for Gynecologic Investigation, 13(2), 124A-125A
Ellis, D.I. and Goodacre, R. (2006) Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy, Analyst, 131, 875-885. DOI:10.1039/b602376m (Full Text)
Ellis, D.I and Goodacre, R. (2006) Quantitative detection and identification methods for microbial spoilage, In Food Spoilage Microorganisms (Ed. Blackburn, C), Woodhead Publishing, Cambridge, UK, pp. 3-27. (Synopsis and Contents)
Allwood, J.W., Ellis, D.I., Heald, J., Goodacre, R and Muir, L. (2006) Metabolomic approaches reveal that phosphatidic and phosphatidyl glycerol phospholipids are major discriminatory metabolites in responses by Brachypodium distachyon to challenge by Magnaporthe grisea. The Plant Journal, 46, 351-368. DOI: 10.1111/j.1365-313X.2006.02692.x (Full Text)
Underwood, B.R., Broadhurst, D., Dunn, W.B., Ellis, D.I., Michell, A.W., Vacher, C., Mosedale, D.E., Kell, D.B., Barker, R., Grainger, D.J. and Rubinsztein, D.C. (2006) Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles, Brain, 129(4), 877-886. (Full Text)
Zhao, H.J., Parry, R.L., Ellis, D.I., Griffith, G.W. and Goodacre, R. (2006) Rapid differentiation of Streptomyces isolates using Fourier transform infrared spectroscopy, Vibrational Spectroscopy, 40, 213-218. (Full Text)
Ellis, D.I., Broadhurst, D., Clarke, S.J. and Goodacre, R. (2005) Rapid identification of closely related muscle foods by vibrational spectroscopy and machine learning. Analyst, 130(12), 1648-1654. (Full Text)
Jenkins, T.E., Hayton, D., Ellis, D.I., Bailey, P., Noakes, T.C.Q. and Clark, G.F. (2005) Multi-technique study of silicon dioxide films on 4H-SiC, Recent Research Developments in Physical Chemistry, 8(2005), 1-20.
Kenny, L.C., Dunn, W.B., Ellis, D.I., Myers, J., Baker, P.N and the GOPEC Consortium, & Kell, D.B. (2005) Novel biomarkers for pre-eclampsia detected using metabolomics and machine learning, Metabolomics, 1(3), 227-234. (Full Text)
Kenny, L.C., Dunn, W.B., Ellis, D.I., Myers, J.E., Robinson, A.E., Kell, D.B. and Baker, P.N. (2005)
Novel biomarkers for preeclampsia detected using metabolomics and machine learning.
Journal of the Society for Gynecologic Investigation, 12(2), 355 Suppl. S FEB 2005
Kenny, L.C., Dunn, W.B., Ellis, D.I., Myers, J.E., Robinson, A.E., Kell, D.B. and Baker, P.N. (2005)
Alterations in placental hemodynamics in growth-restricted transgenic mice.
Journal of the Society for Gynecologic Investigation, 12(2), 354 Suppl. S FEB 2005
Dunn, W.B. and Ellis, D.I. (2005) Metabolomics: current analytical platforms and methodologies. Trends in Analytical Chemistry
24(4), 285-294. (Full Text)
Brown, M., Dunn, W.B., Ellis, D.I., Goodacre, R., Handl, J., Knowles, J.D., O'Hagan, S., Spasic, I. and Kell, D.B. (2005) A metabolome pipeline: from concept to data to knowledge. Metabolomics 1(1), 39-51. (Full Text)
Ellis, D.I., O'Hagan, S., Dunn, W.B., Brown, M. and Vaidyanathan, S. (2004) From genomes to systems.
Genome Biology 5(11), 354. (Full Text)
Ellis, D.I., Broadhurst, D. and Goodacre, R. (2004) Rapid and quantitative
detection of the microbial spoilage of beef by Fourier transform infrared
spectroscopy and machine learning. Analytica Chimica Acta 514,
193-201. (Full Text)
Naheed N. Kaderbhai, David I. Broadhurst, David I. Ellis, Royston Goodacre
and Douglas B. Kell. (2003) Functional genomics via metabolic footprint
profiling: Monitoring metabolite secretion by Escherichia coli tryptophan
metabolism mutants using FT-IR and Direct Injection Electrospray Mass Spectrometry.
Comparitive and Functional Genomics 4, 376-391.
(Abstract)
(Full Text)
Ellis, D.I., Harrigan, G.G. and Goodacre, R. (2003) Metabolic Fingerprinting
with Fourier Transform Infrared Spectroscopy. In: Metabolic Profiling:
Its Role in Biomarker Discovery and Gene Function Analysis (Eds: Harrigan,
G.G. and Goodacre, R.)Kluwer Academic, Boston, 2003, pp. 111-124.
(Synopsis and contents and
ordering
info)
Ellis, D.I., Broadhurst, D., Kell, D.B., Rowland, J.J. and Goodacre, R. (2002)
Rapid and quantitative detection of the microbial spoilage of meat by Fourier
transform infrared spectroscopy and machine learning. Applied and Environmental Microbiology
68 (6), 2822-2828.
(PubMed abstract)
(Full text)
Ellis, D.I. and Goodacre, R. (2001)Rapid and quantitative detection
of the microbial spoilage of muscle foods: current status and future trends.
Trends in Food Science and Technology 12 (11), 414-424.
(Full text)
Proceedings:
Grube, M., Clarke, S., Jarvis, R.M., Ellis, D.I., Goodacre, R., Matjuskova, N. and Muiznieks, I. (2003) Studies of mushrooms Lentinula edodes by infrared spectroscopy. The Inaugral Austral-Asian Biospectroscopy Conference (ABC), 3-7 February, 2003.
Grube, M., Goodacre, R., Matjuskova, N., Muiznieks, I., Clarke, S., Jarvis, R.M. and Ellis, D.I. (2003) Nutritional studies of some Lentinula edodes strains by infrared and Raman spectroscopy. 11th European Congress on Biotechnology, 24-29 August, 2003.
Grube, M., Goodacre, R., Jarvis, R.M., Matjuskova, N., Muiznieks, I., Clarke, S. and Ellis, D.I. (2003) Studies of carbohydrate content in Lentinula edodes mycelium by infrared and Raman spectroscopy. XIV Congress of European Mycologists, 22-27 September, 2003.
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Miscellaneous |
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I am a member of the Society for General Microbiology (SGM) and the Institute of Biology
(IoB) and have a variety of interests including
the detection and identification of metabolites using a combination of the many hyphenated analytical
techniques available to our group.
After 11 years in rural Wales (three in Pembrokeshire and eight in Borth, Ceredigion ), I returned to the North-West and now live in a village to the South of Manchester and on the edge of the Cheshire plain.
My interests outside work include: reading (mainly non-fiction), music
(AMG, the best music encyclopaedia
on the web), film (IMDb), visiting places
of historic, cultural or scenic interest, or indeed just fun days out!(Rough Guides), fine beer and ales
(German beer guide to
Manchester), and retaining a sense of humour, ideally via a combination
of one or two of the above (Young Frankenstein).
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Contact Details |
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If you wish to contact me, please use the following contact details:
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School of Chemistry
The University of Manchester
Faraday Building
PO Box 88
Sackville Street
Manchester M60 1QD
United Kingdom
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