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A number of people have suggested that it would be of great
benefit to scientists who are starting to develop a detailed
interest in the question of what the inside of cells is
really like, and in the (probably) related questions
of the organisation of metabolic channeling and the control of
metabolic fluxes, to have access to a short bibliography that
would serve to outline most of the issues, and to summarise the
evidence that leads many to believe that the inside of a cell
is far more organised than textbooks usually credit. There
follows a short and necessarily eclectic selection that we
believe will be helpful. indicates what might be considered
the first 5.
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Welch, G. R. (1977). On the role of organized multienzyme
systems in cellular metabolism: a general synthesis. Prog.
Biophys. Molec. Biol. 32, 103-191.
Srere, P.A. & Estabrook, R.W. (eds) Microenvironments
and metabolic compartmentation. Academic Press, New York,
1978.
Clegg, J. S. (1984). Properties and metabolism of the aqueous
cytoplasm and its boundaries. Am. J. Physiol. 246, R133-R151
[various] (1984) J.Cell Biol. 99 (No.1, part 2) pp 3S-248S (S
for supplement) "The Cytoplasmic Matrix and Cellular
Function".
Welch, G.R. (ed.) Organized Multi-enzyme Systems: Catalytic
Properties. Academic Press, New York, 1985.
Welch, G.R. & Clegg, J.S. (eds). The Organisation of
Cell Metabolism, Plenum Press, New York, 1986.
Welch, G.R. (ed) The Fluctuating Enzyme, Wiley, New
York, 1986.
Srere, P. A. (1987). Complexes of sequential metabolic
enzymes. Annu. Rev. Biochem. 56, 21- 56.
Westerhoff, H.V. & van Dam, K. Thermodynamics and
Control of Biological Free-energy Transduction. Amsterdam:
Elsevier, 1987.
Jones, D.P. (ed.), Microcompartmentation. CRC Press,
Boca Ration, FL, 1988.
Srere, P., Jones, M.E. & Mathews, C. (eds) Structural
and organizational aspects of metabolic regulation, UCLA
Symposia on Molecular and Cellular Biology, New Series, Vol 134,
Alan R. Liss, New York, 1990.
Cornish-Bowden, A. & Cárdenas, M.L. Control of
metabolic processes. NATO ASI Series Vol 190. Plenum Press,
New York, 1990.
Ovádi, J. (1991). Physiological significance of metabolic
channelling. J. Theoret. Biol. 152, 1-22 (and some, but by no
means all, of the papers in this special issue of JTB).
Stadtman, E.R. & Chock, P.B. (eds) From metabolite to
metabolism to metabolon. Current Topics in Cellular
Regulation Vol 33. Academic Press, New York, 1992.
Brindle, K. (ed.) Enzymology in vivo (Adv. Mol. Cell.
Biol. 11) JAI Press, London, 1995.
Kacser, H., Burns, J.A. & Fell, D.A. (1995) The control of
flux. Biochem. Soc. Trans. 23, 341- 366
Ovádi, J. Cell architecture and metabolic channeling.
Springer-Verlag, New York, 1995.
Fell, D.A. Understanding metabolic control. Portland
Press, London, 1996.
Heinrich, R. & Schuster, S. (1996) The Regulation of
Cellular Systems. Chapman & Hall, New York.
A summary of the abundant evidence that bulk-phase
chemiosmotic coupling does not serve to account for energy
transduction in oxidative and photosynthetic phosporylation may
be found in Kell, D.B., Protonmotive energy-transducing systems:
some physical principles and experimental approaches. In: Bacterial
Energy Transduction (C.J. Anthony, ed.), pp. 429-490.
Academic Press, London, 1988.
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Suggestions for amendments to the canon are welcome, but there
is a rule that says that you can't suggest your own publications!
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Last update: 19 February 2004
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